Knee Pain After Running? Your Genetic Code Has the Solution

 A man on a running track

As a runner, you know the thrill of pushing your limits and the satisfaction of crossing the finish line. But what happens when nagging knee pain threatens to sideline your passion?

Before you resign yourself to a life of ice packs and painkillers, consider this: your genetic code may hold the key strategies to prevent sore knees and optimize running performance.

In this post, we'll explore the link between genes, knee health, and running performance. 

We'll also introduce you to GENEFIT, a cutting-edge app that provides personalized insights and gene-informed running plans to help you achieve your running goals pain-free- and optimize performance.

Let's begin.

How Genetics Influence Knee Health

Have you ever wondered why some runners' knees can handle marathon after marathon while others develop knee pain after just a few training runs? 

Several factors, like training errors, wearing the wrong shoes, and weak muscles, can lead to knee problems. However, genetic factors play a prominent role in determining your risk of developing knee pain.

In fact, genetics account for up to 69% of the risk for anterior cruciate ligament (ACL) tears.

Certain genetic variations affect the health of muscles, tendons, ligaments, and bones in your knees. 

This means your risk of knee injuries is partially encoded in your DNA.

Factors That Impact The Root Causes Of Knee Pain

A runner holding their knee due to a sore knee after running.


Understanding why your
knee hurts after running is the first step to getting back on the road to recovery.

Understanding how genes affect joint stability, cartilage health, and tissue repair provides a broader perspective on addressing the root causes.

So, let's explore some physiological pathways that influence knee pain and how your DNA plays a role:

Knee Stability

Genetic variations can significantly affect the stability of knee joints, potentially increasing susceptibility to injury.

Research has identified that COL1A1 is linked to the remodeling and repair of cartilage and ligaments, directly impacting knee stability.

Moreover, individuals with certain genetic profiles may have a higher risk of experiencing knee instability and related issues.


Cartilage and Tendon Health

Cartilage and tendon health significantly influence knee pain during running, affecting joint stability, shock absorption, and overall injury susceptibility.

Certain genes influence the body's ability to maintain and repair cartilage and tendons, including:

These genetic factors can affect how well knee joints handle stress and recover from injuries.

Recovery and Repair Efficiency

Recovery and repair efficiency influences knee pain during running by affecting healing speed, nutrient delivery, and tissue recovery from stress.

Genetic differences can impact the efficiency of recovery from knee stress or injuries. A key gene in this process is VEGFA (Vascular Endothelial Growth Factor A).

It is crucial for blood vessel formation. Variations in VEGFA can affect how well tissues receive necessary nutrients and oxygen during the repair process.

These differences can lead to variations in recovery efficiency, impacting how quickly knee injuries heal.

Using Genetic Testing to Identify Knee Injury Risks

Genetic tests pinpoint the causes of knee pain while running


Knee pain and injury are extremely common in runners. The knee joint bears the brunt of the impact during running, making it highly susceptible to overuse injuries.

In fact, a systematic review found that the knee accounted for 28% of running injuries, with a higher proportion in women (40%) compared to men (31%).

However, by using genetic testing, runners can identify their individual risk factors for injuries and take proactive steps to prevent them. Genetic tests can provide insights into specific genes related to joint and cartilage health, as well as inflammation and repair processes.

An analysis screens your genetic code for these risk variants. The results allow you to take preventative action through targeted nutrition and training adaptations.

For example, if you have risk variants for poor connective tissue health, your training coach can guide you on strengthening exercises, recovery strategies, and key micronutrients to support your joints.

Avoid training setbacks with our injury risk alerts.

🧬 Download the GENEFIT App today!

 

How Traditional Training Can Exacerbate Knee Pain

If you're experiencing knee pain after running, a traditional training approach can aggravate the issue. Here's how:

Ignoring Genetic Predispositions

Generic training plans treat all runners the same, assuming a one-size-fits-all method will work. 

However, science shows genetics impact 66% of your athletic potential and injury risk. 

Genetics highlights individual focus areas such as recovery needs and injury predispositions. This paints a picture of what types of workouts your body responds to best. 

Generic run programs, on the other hand, follow a very 'traditional' approach. They don’t account for individual differences and predispositions which can set you up for long-term knee problems.

Consequently, pushing beyond your limits can overtax weak connective and muscle tissues. This, in turn, increases the likelihood of experiencing a knee injury.

What follows? You may be set back weeks or even months!

The Cycle of Recurring Issues

Traditional training doesn’t target sore knee after running


Not paying attention to your genetic predispositions while you’re powering through your training could land you in a loop of knee troubles that may become chronic.

Most often the solution is sought in treating the symptoms. However, the root cause of the problem is seldom understood or addressed.

This on-again, off-again pattern can lead to frustration and hinder progress.

Genetic insights may help to break this frustrating cycle of persistent knee pain. 

GENEFIT uncovers how.

Improving Knee Health & Preventing Injury: The GENEFIT Way

Lower injury risk translates into consistent training, faster race times, and achieving your personal bests (PBs) pain-free. 

Who wouldn't want that?

With GENEFIT, you can now get real-time injury forecasting and personalized recommendations that can help alleviate injury risk and enhance recovery. This helps further support your efforts, improving how your body adapts to training.

Genetics Testing

What if you had a personalized roadmap to chart your peak performance and monitor periods of increased injury risks through real-time alerts? 

With GENEFIT's genetic testing, that's precisely what you'll get.

The test screens your DNA across six core performance categories:

  • Training Response
  • Recovery
  • Injury
  • Body Composition
  • Energy Levels
  • Nutrients

Within each category, your genes are assessed in certain genetic pathways to determine your unique strengths and weaknesses. This genetic profile empowers you with the knowledge to train smarter, stay injury-free, and achieve your peak potential.

Analyzing Injury Risks With VISIONARY's Injury Alerts

GENEFIT’s Injury Alerts help prevent muscle and connective tissue injury.

VISIONARY
is GENEFIT's cutting-edge intelligent agent that continually monitors your training load, recovery capacity, and genetic injury risks to predict your real-time risk of injury.

 

After every training session, VISIONARY analyzes the impact on your Muscle Health and Connective Tissue Health, indicating your level of risk. It does this through a colored traffic light system and a corresponding score.

Here’s what GENEFIT’s Injury Alerts look like:

Interpreting Injury Alert Scores To Prevent Knee Pain

Consistently monitoring your Injury Alert scores allows you to gauge tissue health and tweak training intensity when at risk.

While GENEFIT does not offer knee-specific injury insights, maintaining muscle and connective tissue health scores in or close to green translates into more resilient and pain-free knees.

Genetically Informed Recovery Strategies

Beyond informing your training practices, GENEFIT offers tailored daily nutritional tips and lifestyle recommendations based on your training load, genetics, and injury risk.

These science-backed recommendations help optimize your recovery, promoting optimal fitness adaptations and enhancing injury resilience.

For example, suppose you have a genetic predisposition to post-training inflammation. In that case, GENEFIT may encourage you to take a shot of vegetable juice mixed with a teaspoon of ginger, turmeric, or cinnamon after a particularly intense training session. 

This combination can help reduce excessive post-training inflammation after exercise, minimizing soreness and enhancing recovery.

Implementing these personalized diet, lifestyle, and training strategies helps your body to adapt and thrive while running, likely allowing for improved healing and recovery. 

Running Smarter With GENEFIT's Training Plans

The knee joint bears the brunt of 3-4 times your body weight with each stride. 

It’s no wonder that repetitive impact from running mile after mile can lead to inflammation, cartilage damage, and pain. 

This underscores the importance of training with your genes instead of against them.

Pre-Built Run Training Plans From 5Ks to Marathons

GENEFIT came up with a revolutionary approach to traditional running - customized, gene-informed running training plans.

The app offers pre-built plans, from 5Ks to full marathons. 

Just enter the following data on the GENEFIT app:

  • Sport
  • Goal distance
  • Fitness level
  • Starting week
  • Preferred rest day
  • Any existing injuries.

Once logged, GENEFIT’s algorithms generate a full training calendar optimized to your genetic profile. All the guesswork of building fitness while protecting vulnerable knees is done for you.

Note: If you wish to use your own training regime, GENEFIT could still be of great help, offering insights through fitness metrics and unplanned session scores to guide training efforts.

Real-Time Feedback With Session Scores

After each workout, GENEFIT tracks your performance with a simple 1-100 Session Score.

The Session Score rates how well you executed the prescribed workout with a high score in the green indicating high-quality adherence and workout productivity.

Gene-Informed Training - A Leap Toward Peak Performance

GENEFIT’s Injury Alerts help prevent muscle and connective tissue injury.


In essence, new innovations in genomics now enable us to unlock the secrets hidden in our DNA to guide our fitness journeys like never before. 

To help further the same, GENEFIT is revolutionizing how athletes approach their fitness goals. It utilizes the latest advancements in sports genetics and advanced technology to help propel your run performance to new heights, pain-free.

So don’t just train hard. 

Train smart, with the guidance of your genes.

Discover how personalized genetics can transform your active lifestyle at GENEFIT.

Download the app now!

FAQs

How is runner's knee treated?

Runner's knee is treatable with proper treatment and care including:

  • Rest well
  • Stretching and strengthening exercises
  • Physical therapy 
  • Strapping
  • Orthotics
  • Bracing

Finally, understanding why your knees hurt after running based on your genes can help customize treatment for long-term relief.

How long does a runner's knee last?

If left untreated, runner’s knee can last for months or years, leading to chronic knee problems. Using a holistic approach like gene-based guidance, braces, targeted exercises, and nutrition can often resolve knee pain after running within 6-8 weeks.

Can I walk with a runner's knee?

Walking gently with runner's knee is usually fine and can aid recovery. But take care not to overdo it and avoid any activity that causes pain. If you experience pain, rather revert to more rest, continuing with prescribed therapy.

Check with your physician, and consider cross-training which offers cardio alternatives while removing running stress from your knee.

Does running make knee pain go away?

Running through knee pain often makes it worse, further damaging tissue. Rather pre-empt knee pain through training wisely, ramping your run training up using your genetics as a guide

Building leg strength and incorporating cross-training also aids in building injury resilience, helping to avoid knee pain when running.